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Surgical Closure of Patent Foramen Ovale in Cryptogenic Stroke Patients Stroke 28:2376-2381, Homma,S.,et al, 1997 See this aricle in Pubmed Article Abstract Although PFO is easily repairable in patients with cryptogenic stroke,its closure does not consistently prevent recurrence of ischemic events.The recurrence appears to occur more frequently in older cryptogenic patients.

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